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Avoid use in patients with a personal or family history of MTC or those with MEN 2

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Specification: Appearance: White crystalline powder

Brief receptor occupancy with short-acting GLP-1 RAs could explain the transient effect on HR, while prolonged receptor occupancy could explain the more pronounced HR effect observed with some long-acting GLP-1 RAs

To in response to these challenges, prodrug-based nanoparticulate drug delivery systems (PNDDS), which combines prodrug strategy and nanotechnology into a single system, resulting their many advantages, including stability for prodrug structure, the higher drug loading capacity of the system, improving the target activity and bioavailability, and reducing their untoward effects