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Additionally, they reported the synthesis of the decapeptide Aib-ACP (H-Val-Gln-Aib-Aib-Ile-Asp-Tyr-Ile-Asn-Gly-NH 2 ) (Figure 20), replacing DMF with THF and ACN and exploiting SPPS methodology on the polyethylene glycol resin ChemMatrix

In addition, the substrate and product of glutaminase reaction, glutamine and glutamate, respectively, can work as signalling molecules moderating redox and bioenergetic pathways in cancer

FARMACOCINTICA Y FARMACODINAMIA: Absorcin: Presenta una biodisponibilidad del 5%

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