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Since they are not FDA-approved, they do not have standardized FDA-required labeling, including side-effect warnings, boxed warnings, or risk evaluation and mitigation strategies that apply to approved drugs

The purpose of this review is to evaluate the importance of the transsulfuration pathway in these cells, particularly in the context of a reserve pathway that channels methionine towards cysteine when the demand for glutathione is high, or under conditions in which the supply of cystine by the x c exchanger may be compromised

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