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In such a way that unoxidized fatty acids are rerouted toward the synthesis of diacylglycerol and ceramide, which in turn stimulate stress-induced protein kinases that inhibit insulin signaling ( Despite these two hypotheses

Neurology 67 , 878880 (2006)

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The OA mice were randomly divided into three treatment groups ( n = 6 per group): (1) PBS, (2) CuS NPs, and (3) B2M-CuS NPs