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Persistent constipation, significant abdominal swelling, severe pain, or vomiting should be evaluated rather than treated as routine constipation

A missense mutation in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus

Fertility of male or female rats was unaffected by metformin when administered at doses as high as 600 mg/kg/day, which is approximately 2 times the MRHD based on body surface area comparisons

Scheduled tanning beds are not recommended during active weight loss, as the combination of concentrated UV exposure and metabolic stress increases skin damage risk

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion