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Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis

Randomized patients (shown) do not include 99 patients that discontinued during the 20-week run-in period

Basal Rates Some patients need slightly lower basal rates over time, especially if fasting lows occur or if meals are skipped more often

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Potential for Dependency: Reliance on medication may hinder the development of long-term lifestyle changes