All three were able to be co-cultured with primary hGEC from the same donor as hpPOD inside the GOAC, although hiPOD evidenced a less organized nephrin distribution, lower secretion of matrix proteins, such as collagen IV and laminin, and lower efficiency of permselectivity, which exalts the relevance of shifting away from using cell lines in OoC models
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While glutathione is widely known for protecting cells from damage, the team found that cancer cells can hijack it and use it as a nutrient, particularly in environments where other resources are scarce
A human genetic disease characterized by CPT2 deficiency leads to elevated acylcarnitine levels in serum caused by impaired FAO
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