Denatured peptide molecules lose their biological activity
(PubMed) Ma JL, Zhang L, Brown LM, et al
Because cuproptosis preferentially targets cells with high oxidative phosphorylation (OXPHOS) dependency, whereas glycolytic tumors remain relatively resistant, it exposes a distinct metabolic vulnerability in cancer and presents unique therapeutic opportunities 165,166
The atherosclerotic benefits provided by GLP-1RA, which reflect the improvement of glycated hemoglobin level, blood pressure, albumin-to-creatinine ratio and other favorable hemodynamic effects, may be responsible, at least in part, for this finding
doi: 10.1093/humupd/dmp008 142 MoranLJTassoneECBoyleJBrennanLHarrisonCLHirschbergALet al
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