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It is hoped that tau-targeted ASOs may slow or halt neurodegeneration by preventing the aggregation of hyperphosphorylated tau into neurofibrillary tanglesbelieved to be a key driver of neuronal lossand the spreading of tau across neural networks (seeding)
Treatment is not based on patient request alone
For people using it alongside semaglutide, the dosage may be adjusted to match the timing of when they experience the most nausea, such as shortly after taking semaglutide
Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A