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Validation studies showed that the absolute biases for the quality control (QC) samples at the low, medium and high levels were 0.6%, 5.0% and 5.6% in plasma, and 4.6%, 9.0% and 7.0% in urine, respectively

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Already in 1923, German pathologist Friedrich Lewy described perivascular iron deposits in postmortem PD brains 201

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