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2022 doi: 10.1111/ajt.17035

All in all, definitely a goodie for oily, acne-prone skin

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In contrast, when tissue folate or cobalamin stores are intact (Silberberg et al, 1997) or in the case of an alteration of the transsulfuration pathway dependent on vitamin B 6 deficiency or on heterozygosity for a CBS defect (Bostom et al, 1995a), an excessive methionine supply might lead to an important elevation of plasma homocysteine

Your dental team can recommend the most appropriate fluoride regimen based on your individual risk factors