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While not required, following a balanced, low-calorie diet can enhance results

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Aquilano, et al., Front

McFadyenJDKieferJBraigDLoseff-SilverJPotempaLAEisenhardtSUet alDissociation of C-reactive protein localizes and amplifies inflammation: evidence for a direct biological role of C-reactive protein and its conformational changes

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Excess sebum combines with dead skin cells and bacteria, leading to clogged pores and acne formation