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Matsushita K et al

Which means it is possible, in principle, to design molecules that produce the parts of the GLP-1 effect that you want (appetite suppression, glycemic control, cardiovascular benefit) while minimizing the parts that you do not (gastrointestinal misery, certain forms of receptor downregulation, possibly some of the off-target effects we are still characterizing)

Some people using Mounjaro injection may notice temporary menstrual changes such as spotting or slight cycle irregularity

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& Libby, P