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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that works by mimicking GLP-1, a naturally occurring hormone, to manage blood sugar levels and promote weight loss through several mechanisms: Delaying gastric emptying to prolong fullness and reduce hunger
Many notice improvements in blood pressure, energy, joint comfort, and clothing fit
Martha Viera, MD References National Library of Medicine, 2024, Glucagon-Like Peptide-1 Receptor Agonists Sofwave, Lost Weight, Gained Loose Skin or Muscle Loss
There is also a risk of dehydration due to gastrointestinal complaints and reduced food and fluid intake
A subset of patients find that their body's response plateaus on tirzepatide after initial success, or they achieve their goal weight and seek a maintenance-phase medication with potentially milder side effects
What if I'm consistently under-eating and can't reach my macro targets
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