While GLP-1 agonists work well for controlling blood sugar and helping with weight loss, its important to remember that they arent suitable for everyone, including pregnant individuals or those with certain pre-existing health conditions, like a history of pancreatitis
Dosing typically starts at 0.25 mg weekly for diabetes management, with gradual escalation to maintenance doses of 0.5 mg, 1 mg, or 2 mg depending on glycemic control and tolerability
Naltrexone-bupropion ( Contrave ): Constipation has been reported in over 19% of people taking Contrave
Can You Get Semaglutide Delivered to Your Home
Thyroid C-Cell Tumours Boxed Warning (Both Drugs) Both semaglutide and tirzepatide caused thyroid C-cell tumours in rodent studies
The final point to note in this section on SGLT2 inhibitors is that, for those with established or high risk of CVD who are unable to tolerate an SGLT2 inhibitor, the recommendation is for them to remain on metformin alone