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As we age, the bodys ability to synthesize glutathione diminishes

also suggest that modifications that reduce the peptides affinity for IGF-binding protein may support an increase in the amount of free, bioactive IGF-1 available at tissue sites

Methods We enrolled 47 CAD patients in the study

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Thus, the use of this approach allowed to identify an original target, the protein kinase DYRK1B, suggesting that an inhibitor of this protein could present a possible senolytic activity 40