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The central mechanism is angiogenesis: the peptide upregulates vascular endothelial growth factor (VEGF) and drives new blood-vessel formation at injury sites, which brings oxygen and nutrients to healing tissue

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GLP-1 receptor agonists significantly lowered CRP levels (standardised mean difference of 0.39) and TNF- levels (SMD of 0.51), with longer treatment durations yielding more noticeable benefits, according to a thorough meta-analysis published in 2025 that synthesised 25 studies involving 1,878 patients with type 2 diabetes

Kerbler SM, Armijos-Jaramillo V, Lunn JE, Vicente R