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Heres why: The first four weeks are an adjustment period Wegovy builds up to therapeutic levels gradually

Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at The authors have no conflicts of interest to declare

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Our findings, together with recent reports that astrocytes regulate synapse formation and synaptic transmission, reinforce the emerging view that astrocytes have an active regulatory rolerather than merely supportive roles traditionally assigned to themin the mature central nervous system

Data curation: Ole K

All ADMs were compared for use from within 90 days preconceptionally to the end of the first trimester of pregnancy