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Bergenstal RM, Wysham C, Macconell L, Malloy J, Walsh B, Yan P, et al

Combined with the D+Q associated reduction in ventricle size as assessed by MRI, a surrogate measure of neurodegeneration, the data suggested that clearing senescent cells was beneficial for neuronal preservation

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This triple-agonist approach enables researchers to study the combined effects of appetite regulation, insulin secretion, and energy expenditure in a single molecule, making it uniquely valuable for obesity models, metabolic syndrome research, and studies exploring synergistic receptor interactions beyond what dual agonists can achieve