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Figure 2 5.1 Quality of life Patients with pituitary adenomas have been shown to demonstrate a lower quality of life (QoL) ( 5.2 Hypopituitarism In the Iglesias study, hypopituitarism at the time of PRLoma diagnosis was found in about 75% of patients and was more frequently diagnosed in patients with macro- than microPRLomas ( Nevertheless, resolution of HH in patients with macroPRLomas is obtained in a significant proportion of cases upon DAs treatment and PRL normalization