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Of note, we found that, while acute stimulation of GLP-1R in LH was highly effective at food intake and body weight gain suppression, acute blockade was not sufficient to alter chow intake or body weight

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Disclosure of interest: RJvO and WHvZ report financial support for the current manuscript from the Collaboration for New Treatments of Acute Stroke (CONTRAST) consortium (which was financed for the current study by the Netherlands Cardiovascular Research Initiative, an initiative of the Dutch Heart Foundation, the Netherlands Brain Foundation, Stryker, Medtronic, and Cerenovus), all paid to their institution

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Goldstein, A.L

Never overlap both medications Taking semaglutide and tirzepatide simultaneously is not recommended by any clinical guideline