A new 2026 study clarifies the muscle loss issue
Pfizer's decision to halt development of the drug came after "a review of the totality of information, including all clinical data generated to date for danuglipron and recent input from regulators," according to a release
The combined appetite-suppressing effects can lead to insufficient caloric and nutrient intake
Without resistance training, that deficit leads to indiscriminate weight loss that includes significant muscle mass
[6][7] Examples of healthy fats include: Studies show that carbohydrates that keep blood sugar levels stable may also help support GLP-1 activity
"They've helped improve diabetes care and obesity treatment in ways we haven't seen before." Why weight matters for men's health Excess weight, particularly around the abdomen, increases the risk of conditions that disproportionately affect men, including Type 2 diabetes, high blood pressure, sleep apnea, and cardiovascular disease