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Aug 2020;31(8):570-579

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For preventing side effects caused by valproic acid (Depacon, Depakene, Depakote, VPA): 150-500 mg/kg has been taken daily

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The same study also showed that Sema markedly reduced glucose area under the curve (AUC) over a standardized meal test, highlighting its ability to improve glycemic response through coordinated pancreatic and gastrointestinal effects