Food and Drug Administration (FDA) announced on January 28th, 2025, that Ozempic (semaglutide, Novo Nordisk) is now approved to reduce the risk of kidney disease worsening, kidney failure, and death from cardiovascular disease in adults with type 2 diabetes and chronic kidney disease (CKD)
Severe GI events that required dose reduction or treatment discontinuation were relatively rare
In native GLP-1, DPP-4 cleavage occurs precisely at position 8 - the site where Aib now resides in semaglutide
For example, hypoglycemia (low blood sugar) can lead to headaches
You are skipping the doses
When comparing semaglutide to traditional asthma treatments, several points stand out