99 The anti-inflammatory effect of GLP-1 also occurs in diabetes-induced neuroinflammation
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The pharmacological innovation of semaglutide lies in its ability to bind to the GLP-1 receptor with high affinity, thereby enhancing insulin secretion in a glucose-dependent manner, reducing glucagon secretion, and delaying gastric emptying
10.1113/jphysiol.2013.254862 J
Specific genetic variations, including changes in certain genes, are associated with a higher risk of type 2 diabetes
Finally, semaglutide decreases the release of another hormone called glucagon