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If approved, we believe pemvidutide could offer an important option for obesity patients, including those with risk factors for cardiovascular disease. However, tolerability issues remain, as the trial led to one participant experiencing vomiting, and 4.1% of the patients in the drug cohort discontinuing treatment in the first 16 weeks, when compared to 2.1% in the placebo group
The tissue feels better but not stable
However, the long-term consequences of CVD outcomes regarding OCA need to be explored
Toniolo A, Fadini GP, Tedesco S, et al
Additionally, about 28% of users discontinue therapy due to side effects such as nausea and gastrointestinal discomfort
[DOI] [PMC free article] [PubMed] [Google Scholar] Stone NJ, Robinson JG, Lichtenstein AH, Bairey Merz CN, Blum CB, Eckel RH, et al
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