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Neither cagrilintide nor retatrutide is currently licensed in the UK, so neither is available through NHS or private prescribing routes

This also serves as a proof of concept for future pharmacogenomic studies to illuminate the broader set of genes and pathways involved in GLP1R agonist effects

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Normally, lysophosphatidylcholines (LPCs) and phosphatidylcholines (PCs) maintain membrane fluidity, facilitate neurotransmitter release, and regulate immune homeostasis

The selection process is illustrated in the flow diagram ( Figure 1 )