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Glutathione is also widely used in cosmetic and skincare products for skin brightening and reducing hyperpigmentation, thanks to its ability to inhibit melanin production

doi: 10.3390/nu12113443 490 KalilACThomasPG

Furthermore, FOXO4-DRI targets the tumor suppressor p53, a crucial protein, which may lead to various side effects in clinical trials 37

However, its clinical utility is limited by safety concerns linked to prolonged benzodiazepine exposurespanning cognitive effects, falls and fractures, physiologic dependence, pneumonia, and respiratory complicationswith particularly heightened vulnerability in older adults and those with sleep-disordered breathing, and with long-term use associated with increased all-cause mortality 27,28,29,30,31