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Lackowicz JR

Permission to use the MoCA was provided by Dr Ziead Nasreddine

Notably, in these studies, the upregulation of GPx4 has been achieved by using exogenous agents (like NVP-AUY922, Bafilomycin A1, PD151746, GsMTx4, epigallocatechin-3-gallate, total flavonoids of Engelhardia roxburghiana leaves, Lycium barbarum polysaccharide-glycoprotein, perillaldehyde, melotonin, ferulic acid, and sphingosine-1-phosphate) which either inhibit the degradation of GPx4 or increase its transcription by activating the Nrf2 [67]

In this study, by collecting clinicopathological data from patients receiving adjuvant chemotherapy, we found that high GSH intake increases the risk of recurrence after adjuvant chemotherapy

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Baseline Antioxidant Levels Individuals with high oxidative stress may take longer to restore balance