Patient monitoring should include: Baseline lipid panel, hemoglobin A1c, and liver function tests Blood pressure monitoring (GLP-1 agents typically reduce systolic BP by 3-5 mmHg) [10] Assessment for gastrointestinal adverse effects during dose titration Evaluation for contraindications (personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2) [1] [3] Monitoring for gallbladder disease (increased risk with rapid weight loss) In patients with diabetes and retinopathy, monitoring for worsening eye symptoms, particularly with rapid glycemic improvement Renal function assessment, especially if severe gastrointestinal symptoms cause dehydration Patients should seek immediate medical attention for severe abdominal pain, which may indicate pancreatitisa rare but serious adverse effect
Inside the body, the medications work by mimicking hormones released by the gut after eating, helping regulate blood sugar, slow digestion and keep people feeling full longer
Liraglutide 3.0 mg for the management of insufficient weight loss or excessive weight regain post-bariatric surgery
doi: 10.1161/CIRCULATIONAHA.118.036418 42 MarsoS
These medications, widely prescribed for diabetes and weight loss, have been linked to severe side effects, prompting a surge in legal action
In this case, the activation of 2AMPK by glucose mediates the activation of VMH GI neurons, as described by Murphy et al
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