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L-carnitine is a natural amino acid derivative that actively participates in the transport of fatty acids into the mitochondria, where they are converted into energy, thus supporting optimal function of muscle cells

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For example, erythematous patches, papules, and plaques have been reported (with a median onset of 2 months) in an estrogen- and progesterone-receptor-positive BC patient receiving anastrozole ( Given the confirmed association between dermatologic AEs and AIs such as anastrozole, exemestane, and letrozole, it is essential to clarify the relationship between specific AI agents and dermatologic AEs

Similarly, knockdown of TMLHE decreased multiple histone acetylation marks, many of which were rescued by l-carnitine (Extended Data Fig