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By lowering blood sugar, the GLP-1 drugs can help protect the kidneys from this detrimental effect, which may delay or prevent kidney disease and kidney failure

Only a head-to-head randomized controlled trial could definitively establish superiority, and that trial has not been conducted

doi: 10.1111/nure.12091 103 GammoneMADOrazioN

This is partly metabolic, as the body adjusts to new hormonal signaling, and partly caloric, as reduced food intake means less available energy

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