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The approval was based on LDL-C lowering data from the PROFICIO program

While some individuals use these medications intermittently based on financial constraints, this approach lacks robust evidence and may compromise outcomes

Some patients experience oscillating side effects (nausea in week one, increased hunger in week two) when dosing is irregular, making the treatment harder to tolerate and less effective

This can contribute to issues like poor blood sugar control, increased hunger, and weight gain

Ozempic and Rybelsus are approved for treatment of type 2 diabetes, but they have shown effectiveness in weight loss and reducing the risk of heart attack and stroke

Multilayer nanoparticles for sustained delivery of exenatide to treat type 2 diabetes mellitus