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Nature Cell Biology , 24 (6), 896905

Curr Neuropharmacol , 2020

This occurred even though only 12.4% in the analysis had a B12 insufficiency (meaning they were at the borderline for a deficiency), and only 3% had a B12 deficiency

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In a healthy state, ECs in the CNS exhibit significantly reduced expression of these molecules compared to their peripheral counterparts, further tightly controlling the infiltration of immune cells entry into the brain tissue [34, 35]