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471 According to the PAKT trial, the addition of the AKT inhibitor capivasertib to the first-line paclitaxel therapy for TNBC resulted in significantly longer PFS and OS, especially in tumors with PIK3CA/AKT1/PTEN alterations

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When cancer cells relied on GSH for cysteine acquisition, they were more sensitive to GGsTop 43 , a putative inhibitor of GGT activity (Fig

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Thymosin Alpha-1 has also been shown to enhance vaccine response and help people with severe COVID possibly by repairing damage caused by inflammation

Additionally, metformin has been shown to be effective in reducing pregnancy-related complications in patients with PCOS, including gestational diabetes, hypertension, and preeclampsia