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Ethics statement The animal study was reviewed and approved by University College Cork Animal Experimentation Ethics Committee

In addition, GLP-1 has significant effects on the nervous system [4, 5]

Activation of Sirtuin Pathways (SIRT1) Sirtuins are a family of proteins that regulate metabolism, inflammation, and cellular aging

2 O predominantly affect glutamatergic transmission by antagonizing NMDA receptors (NMDARs), causing excitotoxicity, mitochondrial dysfunction, and neuronal apoptosis

In addition to healthy lifestyle practices like stress management, proper sleep hygiene, and physical activity, ensuring youre also meeting your nutrient requirementseither through food or supplementationis a non-negotiable

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