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Are there any risks or side effects associated with GLP-1 medications

decreased leptin, peptide YY, cholecystokinin, amylin, insulin and glucagon-like peptide-1) 31 , compensatory changes to energy homoeostasis (decreased energy expenditure due to reduced body mass and enhanced metabolic efficiency) 32 , altered nutrient metabolism that can alter energy homeostasis 33 ) and subjective changes in appetite (e.g