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The American Diabetes Association (ADA) recommends [archived link] GLP-1 RAs as first-choice Type 2 diabetes medication options in many cases

Quick Answer: GLP-1 medications should be injected into the fatty tissue on the back of the upper arm, approximately halfway between the shoulder and elbow, using proper subcutaneous injection technique

S5B) 21,22,23

Several classes of peptides interact directly with these immune mechanisms

In addition, the analysis of the EXSCEL trial revealed that a composite end-point of new macroalbuminuria, 40% eGFR decline or renal death was reduced by the addition of exenatide in T2DM [26]