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This creates a frustrating cycle where treating diabetes worsens one of its underlying causes

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To minimise confounding effects, we compared GLP-1RAs with second- or third-line glucose-lowering medications

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In addition to GLP-1 agonists, there have also been recent developments in oral GLP-1 therapies, dual agonists (GLP-1 and/or glucose-dependent insulinotropic polypeptides), and expanded therapeutic uses