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To exclude any effects associated with the procedure used for generation of a new monoclonal sub-clone, wild-type HepG2 cells were treated with varying concentrations of NFT or DEM for 24 h, fixed, and subjected to immunocytochemistry to visualize Nrf2 localization (Fig

This event is currently improving despite continued dosing with ALG-000184 and the studys safety oversight committee assessed it as not being related to drug toxicity

Kanamori K, Ahmad SM, Hamid A, Lutfy K

Don't expect significant improvements yet

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