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Elevated LOXL2 expression in estrogen receptor-negative breast tumors is strongly associated with unfavorable outcomes, including poor prognosis, decreased overall survival, and reduced metastasis-free survival, suggesting that LOXL2 could serve as a valuable prognostic marker for metastasis in breast cancer cases
A signal that expands the proliferating MyoD-positive pool while restraining premature myogenin-driven differentiation would, in principle, enlarge the precursor reservoir before repair is finalized