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As this is an observational study (not randomized) we cannot exclude the presence of residual confounding

GLP-1Rs are highly expressed in the frontal cortex, hypothalamus, thalamus, hippocampus, cerebellum, and substantia nigra pars compacta (SNpc) [9, 41]

In a note Monday, JPMorgan analyst Chris Schott said, "more broadly, we continue to see MET-097i as one of several emerging competitors that we believe will take some share" from Eli Lilly and Novo Nordisk over time

(NIDDK) That does not mean they do all the work

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Hypercalcemia was attributed to diffuse osteolytic metastases, and hyperuricemia and acute kidney injury were suspected to be from obstructive uropathy rather than tumor lysis syndrome