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Once inserted into the rectum, the suppository comes into contact with body heat, causing it to dissolve or melt

doi: 10.1186/s12984-025-01695-9 131 LvKZhangSYaoZZhouCXuJ

9) the regions of interests were selected manually on the maps of height

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Building on these core therapeutic mechanisms, Clostridium -based interventions exhibit clear stratified clinical positioning in ADs, with their therapeutic significance defined by evidence maturity and disease-specific pathological characteristics, serving as a complement rather than a substitute for conventional therapies