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Most data come from small case reports or lab studies, which do not prove long-term safety for the fetus

PLoS ONE 9(8):e104079

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Concurrently, clinicians have observed increased conception rates among individuals using GLP-1 RAs, prompting investigation into whether these effects stem from improved metabolic health or direct pharmacologic influences on reproductive physiology

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However, another report demonstrated mitochondrial stress and bioenergetics defects in GPx1 null mice (Esposito et al., 2000)