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PMID: 35309549 Cotter DG et al (2013): Ketone body metabolism and cardiovascular disease
Careful adjudication of suspected cases was necessary to scrutinize details of the symptomatic presentation, the degree of elevation on pancreatic enzymes, and the diagnostic specificity of imaging data (68)
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This triggers broken immune tolerance: Overactivated innate immune cells secrete pro-inflammatory cytokines, CD4 + T cells skew toward pro-inflammatory subsets (T-helper 1 [Th1] cells/Th17), T regulatory cell (Treg) function is impaired, and autoantibodies exacerbate inflammation
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