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GLP-1 therapy can compound this risk

Zhang X, Zheng C, Gao Z, Chen H, Li K, Wang L, et al

808,871873 It is worth noting that the number of cuproenzymes that are resident in cytoplasm tends to be quite small (or zero) in nearly all organisms, with cell-abundant cuproproteins sequestered in intracellular membrane vesicles, e.g., thylakoids, intracytoplasmic membrane structures, 874 e.g., for particulate methane monooxygenase (pMMO), 112 or simply embedded in the plasma membrane with active sites facing out

Abnormal tau-containing filaments in neurodegenerative diseases