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There are also more serious but less common risks that have been documented with prescription GLP-1 medications, including potential risks related to the thyroid, pancreas, and gallbladder

Obesity causes: Hormonal disruption : Excess adipose tissue converts testosterone to oestradiol through aromatase enzyme activity, reducing bioavailable testosterone Increased scrotal temperature : Abdominal fat can raise testicular temperature, impairing sperm production Oxidative stress : Obesity generates reactive oxygen species that damage sperm DNA Inflammation : Chronic low-grade inflammation affects sperm quality and function Studies of bariatric surgery and intensive lifestyle interventions show mixed effects on male fertility

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According to one article[7], Ozempic is also known for a popular 6-week Ozempic plan thats split into two stages and promises significant weight loss

For each subgroup, PSM was conducted separately, followed by the estimation of HRs using Cox proportional hazards models within each stratum

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