For todays newsletter, Im not going to belabor the same stuff that Ive been talking about over and over again, but I will rehash it quickly: These drugs work really well to promote weight loss These drugs have excellent cardiovascular safety When you start patients on low doses and increase slowly, these drugs are very well tolerated When these drugs are used on the correctly selected patient, they cause people to lose predominantly fat rather than muscle My read of the data is that tirzepatide (AKA Mounjaro) is a better drug than semaglutide (Ozempic)
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Ann Neurol 47(5):614624 Iyengar S, Ossipov MH, Johnson KW (2017) The role of calcitonin gene-related peptide in peripheral and central pain mechanisms including migraine
Do Ozempic and Compounded Semaglutide Work the Same Way
Sullivan, M
At the same time, patients needing these procedures often have obesity or diabetes, conditions that increase surgical risk