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doi: 10.1038/s41421-022-00495-y 457 WuS.SongR.LiuT.LiC

2018;5(4):e130

XBP1s drives the expression of genes involved in ER protein folding, ER-associated degradation (ERAD), lipid biosynthesis, and stress adaptation, thereby enhancing tumor cell fitness under proteotoxic conditions

Theoretical concerns worth understanding: The biggest theoretical concern with any telomerase activator is the possibility of accelerating tumor growth in undiagnosed early-stage cancers