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International Journal of Toxicology, 34 (4), 300307

These symptoms could affect hydration status, nutritional intake, and medication absorption

Nausea, fullness, vomiting, reflux, and constipation may become stronger after a dose increase because the digestive system needs time to adjust

The main endogenous ligand for GLP-1R, the 29 amino acid peptide GLP-1(7-36)NH 2 , is highly susceptible to degradation by proteolytic enzymes that rapidly destroy it in the circulation, making it unsuitable as a therapeutic agent (Deacon et al., 1998)

Senescent cells accumulate and release a cocktail of damaging signals known as the senescence-associated secretory phenotype (SASP), which corrupts surrounding tissue

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